The quiet foothills outside Tucson have become the center of a growing mystery after Nancy Guthrie, the 84-year-old mother of NBC “Today” anchor Savannah Guthrie, was reported missing on Sunday, February 1. Authorities say the case is increasingly troubling, with Sheriff Chris Nanos confirming investigators are not ruling out foul play. Neighbors described an unusual surge of activity, including dark vans, patrol cars, and helicopters, as detectives searched the area and reviewed surveillance footage from a narrow early-morning time window.

Residents say the rugged desert terrain makes it unlikely Nancy wandered away on her own. She relies on a cane, lives in an area without sidewalks, and the surrounding foothills are thick with cacti and rocky terrain. Officials have classified her as a vulnerable adult due to fragile health, noting she requires daily medication that could become life-threatening if missed for more than 24 hours. Her keys, phone, purse, and ID were reportedly left behind.

Investigators now consider the home a crime scene, signaling the case has shifted beyond a routine search. Savannah Guthrie, who traveled to Arizona, released an emotional plea thanking supporters and urging anyone with information to contact authorities. As the investigation intensifies, the family and community remain desperate for answers — and hope.